靶标：
Mtrfr
产品别名：
2810006K23Rik； Mtrfr； mitochondrial translation release factor in rescue； mitochondrial translation release factor in rescue； mitochondrial translation release factor in rescue； Probable peptide chain release factor C12orf65 homolog, mitochondrial；
背景信息：
This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants.
