靶标:
1700028K03Rik
产品别名:
SCRE; Spo16; 1700028K03Rik; RIKEN cDNA 1700028K03 gene; RIKEN cDNA 1700028K03 gene; protein SPO16 homolog; synaptonemal complex reinforcing element; uncharacterized protein C1orf146 homolog;
背景信息:
Plays a key role in reinforcing the integrity of the central element of the synaptonemal complex (SC thereby stabilizing SC, ensuring progression of meiotic prophase I in male and female germ cells. Promotes homologous recombination and crossing-over in meiotic prophase I via its association with SHOC1. Required for the localization of TEX11 and MSH4 to recombination intermediates.