靶标：
Pot1a
产品别名：
1500031H18Rik； AI851169； Pot1； Pot1a； protection of telomeres 1A； protection of telomeres 1A； protection of telomeres protein 1； POT1-like telomere end-binding protein； 端粒保护蛋白1；
背景信息：
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
