靶标：
Wtip
产品别名：
Wtip； WT1 interacting protein； WT1 interacting protein； Wilms tumor protein 1-interacting protein；
背景信息：
WTIP may monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype (By similarity).
