靶标：
Rprml
产品别名：
AW049332； Rprml； reprimo-like； reprimo-like； reprimo-like protein；
背景信息：
The reprimo (RPRM) gene family is a group of single exon genes present exclusively within the vertebrate lineage. RPRM genes are expressed across many species and are associated with developmental patterning of the gastrointestinal tract, brain and blood vessels. In humans, who have only RPRM and RPRM-Like (RPRML), the RPRM gene appears to be involved in tumor suppression in tumors of the gastrointestinal tract as well as in multiple other organs. Expression of RPRM is mainly induced by p53 after DNA damage, though expression of this gene has also been associated with expression of p73, another member of the p53 gene family. Upregulation of RPRM results in cell cycle arrest at the G2/M checkpoint. Epigenetic silencing of RPRM, mainly by DNA methylation of its promoter region, occurs at early stages of human cancer.
宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
