靶标:
GOLM2
产品别名:
CASC4; H63; GOLM2; golgi membrane protein 2; golgi membrane protein 2; protein GOLM2; cancer susceptibility 4; cancer susceptibility candidate 4; cancer susceptibility candidate gene 4 protein; gene associated with HER-2/neu overexpression; protein CASC4;
背景信息:
The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene.