靶标：
TXNRD3
产品别名：
TGR； TR2； TR2IT1； TRXR3； TXNRD3IT1； TXNRD3NB； TXNRD3NT1； TXNRD3； thioredoxin reductase 3； thioredoxin reductase 3； thioredoxin reductase 3； TXNRD3 neighbor gene protein； selenoprotein TXNRD3； thioredoxin and glutathione reductase； thioredoxin glutathione reductase； thioredoxin reductase 2 intronic transcript 1； thioredoxin reductase 3 intronic transcript 1； thioredoxin reductase 3 neighbor gene protein； thioredoxin reductase 3 new transcript 1； thioredoxin reductase TR2；
背景信息：
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
