靶标:
AGBL1
产品别名:
CCP4; FECD8; AGBL1; AGBL carboxypeptidase 1; AGBL carboxypeptidase 1; cytosolic carboxypeptidase 4; ATP/GTP binding protein like 1; protein deglutamylase CCP4;
背景信息:
Polyglutamylation is a reversible posttranslational modification catalyzed by polyglutamylases that results in the addition of glutamate side chains on the modified protein. This gene encodes a glutamate decarboxylase that catalyzes the deglutamylation of polyglutamylated proteins. Mutations in this gene result in dominant late-onset Fuchs corneal dystrophy. [provided by RefSeq, Nov 2013],