靶标:
ADGRG4
产品别名:
GPR112; PGR17; RP1-299I16; ADGRG4; adhesion G protein-coupled receptor G4; adhesion G protein-coupled receptor G4; adhesion G-protein coupled receptor G4; G protein-coupled receptor 112; probable G-protein coupled receptor 112; G蛋白偶联受体112;
背景信息:
This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010],