靶标:
APOBEC3H
产品别名:
A3H; ARP-10; ARP10; APOBEC3H; apolipoprotein B mRNA editing enzyme catalytic subunit 3H; apolipoprotein B mRNA editing enzyme catalytic subunit 3H; DNA dC->dU-editing enzyme APOBEC-3H; APOBEC-related protein 10; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H;
背景信息:
This gene encodes a member of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide 3 family of proteins. The encoded protein is a cytidine deaminase that has antiretroviral activity by generating lethal hypermutations in viral genomes. Polymorphisms and alternative splicing in this gene influence its antiretroviral activity and are associated with increased resistence to human immunodeficiency virus type 1 infection in certain populations. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],