靶标：
TPCN2
产品别名：
SHEP10； TPC2； TPCN2； two pore segment channel 2； two pore segment channel 2； two pore channel protein 2； two pore calcium channel protein 2； voltage-dependent calcium channel protein TPC2；
背景信息：
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.
