靶标:
H2AC21
产品别名:
H2AB; HIST2H2AB; H2AC21; H2A clustered histone 21; H2A clustered histone 21; histone H2A type 2-B; histone 2, H2ab; histone cluster 2 H2A family member b; histone cluster 2, H2ab;
背景信息:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015],