靶标:
C3orf62
产品别名:
MAPS; C3orf62; chromosome 3 open reading frame 62; chromosome 3 open reading frame 62; uncharacterized protein C3orf62; male pachynema-specific protein; 3号染色体开放阅读框62;
背景信息:
C3orf62 (chromosome 3 open reading frame 62) is a 267 amino acid protein encoded by a gene that maps to human chromosome 3p21.31. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.