靶标:
GGT2
产品别名:
GGT1; GGT2; gamma-glutamyltransferase 2; gamma-glutamyltransferase 2; gamma-glutamyltranspeptidase 1; glutathione hydrolase 1 proenzyme; gamma-glutamyltransferase 1;
背景信息:
GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008],