靶标:
H2AFJ
产品别名:
H2A-IX; H2AJ; HIST1H2A9; H2AFJ; H2A histone family, member J; H2A histone family, member J; histone H2A.J; H2a/j; buforin I; histone H2A; histone H2A-IX; histone cluster 1, H2A, IX (similar to human histone cluster 2, class H2A genes); H2A组蛋白家族成员J(H2AFJ);
背景信息:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.