靶标：
Gramd2
产品别名：
BC064463； Gramd2a； Gramd2； GRAM domain containing 2； GRAM domain containing 2； GRAM domain-containing protein 2A； GRAM domain-containing protein 2；
背景信息：
Participates in the organization of endoplasmic reticulum-plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calcium homeostasis. Constitutive tether that co-localize with ESYT2/3 tethers at endoplasmic reticulum-plasma membrane contact sites in a phosphatidylinositol lipid-dependent manner. Pre-marks the subset of phosphtidylinositol 4,5-biphosphate (PI(4,5)P2)-enriched EPCS destined for the store operated calcium entry pathway (SOCE).
