基因名:
DSCR4
产品别名:
DCRB; DSCRB; DSCR4; Down syndrome critical region 4; Down syndrome critical region 4; Down syndrome critical region gene 4; Down syndrome critical region protein 4; Down syndrome critical region protein B; 唐氏综合征临界区域蛋白4;
背景信息:
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. This gene is found in this region and multiple transcripts may exist. It is mainly expressed in the placenta. [provided by RefSeq, Jul 2008]