基因名:
Chil3
产品别名:
AI505981; Chi3l3; ECF-L; Ym1; Chil3; chitinase-like 3; chitinase-like 3; chitinase-like protein 3; beta-N-acetylhexosaminidase Ym1; eosinophil chemotactic cytokine; eosinophil chemotactic factor-L; secreted protein Ym1;
背景信息:
Chitinase 3-like 3 gene, also known as YM1 and ECF-L, encodes a precursor protein with 398 amino acid residues with a 21 residue signal sequence. Chitinase 3-like 3 protein is a lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds heparin and G1cN oligomers, and is produced primarily by macrophages during inflammation. It has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils.