Recombinant Lilra6
Recombinant leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 protein
基因名：
Lilra6
产品别名：
7M1； Pira3； Lilra6； leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6； leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6； paired-Ig-like receptor A3；
背景信息：
The LILRs are a family of receptors that regulate the activities of myelomonocytic cells. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 (ILT5) and LILRA6 (ILT8) are highly polymorphic receptors with similar extracellular domains. LILRA6 can signal through association with an activating adaptor molecule, FcRγ, which bears a cytoplasmic tail with an immunoreceptor tyrosine-based activation motif. Analysis of mRNA expression in the major fractions of PBMCs showed that LILRA6 is primarily expressed in monocytes, and its expression level correlates with copy number of the gene.
