基因名：
Serpina1a
产品别名：
Aat-2； Aat2； Dom1； PI1； Spi1-1； Spi1-3； Serpina1a； serine (or cysteine) peptidase inhibitor, clade A, member 1A； serine (or cysteine) peptidase inhibitor, clade A, member 1A； alpha-1-antitrypsin 1-1； AAT； alpha-1 protease inhibitor 1； alpha-1-antiproteinase； alpha-1-antitrypsin 2； serine (or cysteine) proteinase inhibitor, clade A, member 1a； serine protease inhibitor 1-1； serine protease inhibitor A1a； serpin A1a；
背景信息：
Alpha-1-antitrypsin 1-3(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein have been found for this gene.
