基因名：
MCF2L2
产品别名：
ARHGEF22； MCF2L2； MCF.2 cell line derived transforming sequence-like 2； MCF.2 cell line derived transforming sequence-like 2； probable guanine nucleotide exchange factor MCF2L2； MCF2-transforming sequence-like protein 2； dbs-related Rho family guanine nucleotide exchange factor； MCF2变换序列样蛋白2；
背景信息：
MCF2L2 is a 1,114 amino acid protein that contains one spectrin repeat, one PH domain, one DH domain and one CRAL-TRIO domain. Expressed at high levels in brain and also present in testis and pancreas, MCF2L2 is thought to function as a GEF, catalyzing the activation of target GTPases. Variations in the gene encoding MCF2L2 may be associated with an increased susceptibility to type 2 diabetes. Multiple isoforms of MCF2L2 exist due to alternative splicing events.
