基因名:
ABRAXAS2
产品别名:
ABRO1; FAM175B; KIAA0157; ABRAXAS2; abraxas 2, BRISC complex subunit; abraxas 2, BRISC complex subunit; BRISC complex subunit Abraxas 2; BRISC complex subunit Abro1; abraxas brother 1; abraxas brother protein 1; family with sequence similarity 175 member B; FAM175B蛋白;
背景信息:
FAM175B (ABRO1) is a 415 amino acid protein, sharing 39% identity to ABRA1 in the N terminal two thirds of the protein (amino acids 1 to 260), including a coiled-coil domain and a region called the ABR domain. However, ABRO1 lacks the phosphorylated ser-X-X-phe motif of ABRA1 and, unlike ABRA1, does not bind to BRCA1.