基因名：
ECPAS
产品别名：
ECM29； KIAA0368； ECPAS； Ecm29 proteasome adaptor and scaffold； Ecm29 proteasome adaptor and scaffold； proteasome adapter and scaffold protein ECM29； ECM29 homolog, proteasome accessory protein； ecm29 proteasome adapter and scaffold； homolog of yeast Ecm29； proteasome-associated protein ECM29 homolog； ECM29蛋白；
背景信息：
ECM29 is a 1,845 amino acid protein containing twenty-seven HEAT repeats. Localizing primarily to endoplasmic reticulum, ECM29 acts as an adapter or scaffolding protein, binding to the 26S proteasome, motor proteins, and other compartment specific proteins. The N-terminus of ECM29 binds endocytic proteins, including rabaptin, Rab11-FIP4, and VPS11, while the C-terminus binds myosins and kinesins. ECM29 may also play a role in endoplasmic reticulum (ER)-associated protein degradation (ERAD) in addition to other enhanced proteolysis.
