基因名:
SPIDR
产品别名:
KIAA0146; ODG9; SPIDR; scaffold protein involved in DNA repair; scaffold protein involved in DNA repair; DNA repair-scaffolding protein; scaffolding protein involved in DNA repair; DNA支架修复蛋白; KIAA0146蛋白;
背景信息:
Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity.