基因名：
Cyp3a23-3a1
产品别名：
AABR07035343.1； CYP； CYP3A23； Cyp3a1； Cyp3a23/3a1； Cyp3a3； RL33； cDEX； Cyp3a23-3a1； cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1； cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1； cytochrome P450 3A1； CYPIIIA1； Cytochrome P450, subfamily IIIA, polypeptide 3； P450 IIIA； P450-PCN1； cytochrome P-450； cytochrome P-450PCN (PNCN inducible)； cytochrome P450 3A1-like； cytochrome P450, family 3, subfamily a, polypeptide 1； cytochrome P450, subfamily 3A, polypeptide 3； cytochrome P450-PCN1； cytochrome P450/6 beta B； 细胞色素CYP3A1；
背景信息：
CYP3A proteins are P450 monooxygenases and in animals, P450 enzymes serve two major functions: biosynthesis of steroids, fatty acids and bile acids, and the metabolism of endogenous and exogenous substrates. A wide variety of exogenous substrates are metabolized by P450 enzymes, including toxins and drugs. The four major families involved in drug metabolism are CYP1, 2, 3 and 4. The hepatic CYP3A1 protein is detected throughout ciliated and nonciliated cells in seven-day-old rats, and is only detected in the apex of these cells in adult rats. Rat CYP3A1 and CYP3A2 share 89% homolgy, but differ by three out of five of their C-terminal residues.
