基因名:
CPAMD8
产品别名:
ASGD8; K-CAP; VIP; CPAMD8; C3 and PZP like alpha-2-macroglobulin domain containing 8; C3 and PZP like alpha-2-macroglobulin domain containing 8; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8; alpha-2 macroglobulin family protein VIP; CPAMD8蛋白;
背景信息:
CPAMD8 belongs to the complement component-3 (C3; MIM 120700)/alpha-2-macroglobulin (A2M; MIM 103950) family of proteins, which are involved in innate immunity and damage control. Complement components recognize and eliminate pathogens by direct binding or by mediating opsonization/phagocytosis and intracellular killing, and A2M is a broad-spectrum protease inhibitor (Li et al., 2004 [PubMed 15177561]).[supplied by OMIM, Mar 2008]