基因名:
nccrp1
产品别名:
NCCRP-1; wu:fa93e02; wu:fb12f07; zgc:122987; nccrp1; P1, F-box associated domain containing; P1, F-box associated domain containing; F-box only protein 50; NCC receptor protein 1; NCCRP1, F-box associated domain containing; non-specific cytotoxic cell receptor protein 1; nonspecific cytotoxic cell receptor protein 1; 非特异性细胞毒性受体蛋白1;
背景信息:
NCCRP1 is a 275 amino acid protein that contains one FBA (F-box associated) domain. The gene encoding NCCRP1 maps to human chromosome 19q13.2. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.