基因名:
WDR83OS
产品别名:
ASTERIX; C19orf56; PAT-10; PAT10; PTD008; WDR83OS; WD repeat domain 83 opposite strand; WD repeat domain 83 opposite strand; PAT complex subunit Asterix; UPF0139 membrane protein C19orf56; WDR83 opposite strand; protein Asterix; protein associated with the ER translocon of 10kDa; 19号染色体开放阅读框56;
背景信息:
C19orf56 is a 106 amino acid protein that is encoded by a gene located on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.