基因名:
FBXL19
产品别名:
CXXC11; Fbl19; JHDM1C; FBXL19; F-box and leucine rich repeat protein 19; F-box and leucine rich repeat protein 19; F-box/LRR-repeat protein 19; jumonji C domain-containing histone demethylase 1C; FXL19蛋白;
背景信息:
This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]