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重组原钙粘蛋白γB2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Recombinant PCDHGB2
Recombinant protocadherin gamma subfamily B, 2 protein
基因名:

PCDHGB2


产品别名:

PCDH-GAMMA-B2; PCDHGB2; protocadherin gamma subfamily B, 2; protocadherin gamma subfamily B, 2; protocadherin gamma-B2; 原钙粘蛋白γB2;


背景信息:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protocadherein gamma cluster consists of three subfamilies (A, B and C). As a member of the gamma subfamily B, PCDHGB2 (Protocadherin gamma B2) is a 931 amino acid protein that is one of 22 proteins encoded by the protocadherin gamma cluster. Typical of gamma protocadherins, PCDHGB2 contains six cadherin motifs and is a type I transmembrane receptor expressed in the central nervous system. With localization to synapses, members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGB2 that are produced as a result of alternative splicing events.
 
 
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