基因名：
Poglut2
产品别名：
1810049A15Rik； 5730416C13Rik； EP58； Kdel1； Kdelc1； Poglut2； protein O-glucosyltransferase 2； protein O-glucosyltransferase 2； protein O-glucosyltransferase 2； ER protein 58； ERp58； KDEL (Lys-Asp-Glu-Leu) containing 1； KDEL containing protein 1； KDEL motif-containing protein 1； endoplasmic reticulum resident protein 58； endoplasmic reticulum-resident KDEL protein； protein O-xylosyltransferase POGLUT2； 赖氨酸，天冬氨酸，谷氨酸，亮氨酸相关序列；
背景信息：
Endoplasmic reticulum Marker.
The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins (GRP 78) and GRP 94 respectively and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
