重组蛋白酶体β亚基11

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重组蛋白酶体β亚基11

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant Psmb11
Recombinant proteasome (prosome, macropain) subunit, beta type, 11 protein

基因名：

Psmb11

产品别名：

5830406J20Rik； beta5t； Psmb11； proteasome (prosome, macropain) subunit, beta type, 11； proteasome (prosome, macropain) subunit, beta type, 11； proteasome subunit beta type-11； proteasome beta 11 subunit； proteasome subunit beta-5t； proteasome subunit beta5t；蛋白酶体β亚基11；

背景信息：

Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7, and alpha-1 to -7. The catalytic subunits are beta-1 (PSMB6; MIM 600307), beta-2 (PSMB7; MIM 604030), and beta-5 (PSMB5; MIM 600306). Three additional subunits, beta-1i (PSMB9; MIM 177045), beta-2i (PSMB10; MIM 176847), and beta-5i (PSMB8; MIM 177046), are induced by gamma-interferon (IFNG; MIM 147570) and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11, or beta-5t, is a catalytic subunit expressed exclusively in cortical thymic epithelial cells (Murata et al., 2007 [PubMed 17540904]).[supplied by OMIM, Mar 2008]