基因名:
Arhgap36
产品别名:
1100001E04Rik; rho-gap; Arhgap36; Rho GTPase activating protein 36; Rho GTPase activating protein 36; rho GTPase-activating protein 36; RhoGAP domain containing protein; Rho GTP酶激活蛋白36;
背景信息:
ARHGAP36 is a 547 amino acid protein that contains one Rho-GAP domain. Conserved in chimpanzee, dog, cow, mouse and rat, ARHGAP36 exists as five alternatively spliced isoforms and is encoded by a gene that maps to human chromosome Xq26.1. Chromosome X consists of nearly 153 million base pairs encoding approximately 1,000 genes. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are X chromosome-linked conditions that affect males more frequently because males carry a single X chromosome.