基因名:
TRIM46
产品别名:
GENEY; TRIFIC; TRIM46; tripartite motif containing 46; tripartite motif containing 46; tripartite motif-containing protein 46; gene Y protein; tripartite, fibronectin type-III and C-terminal SPRY motif protein; TRIM46蛋白;
背景信息:
TRIM46 is a 759 amino acid intracellular protein that contains a variety of domains that are characteristic to TRIM proteins, including a RING-type zinc finger and a B box-type zinc finger. All subclass members, including TRIM46, TRIM9, TRIM67 and TRIM36, have conserved domain arrangement and associate with microtubule cytoskeleton, which may suggest that subcellular compartmentalization is determined by the unique domain architecture. The gene encoding TRIM46 is located on human chromosome 1, which spans about 260 million base pairs and comprises nearly 8% of the human genome.