基因名:
CRISPLD1
产品别名:
CRISP-10; CRISP10; LCRISP1; CRISPLD1; cysteine rich secretory protein LCCL domain containing 1; cysteine rich secretory protein LCCL domain containing 1; cysteine-rich secretory protein LCCL domain-containing 1; CocoaCrisp; LCCL domain-containing cysteine-rich secretory protein 1; cysteine-rich secretory protein 10; trypsin inhibitor Hl; 富含半胱氨酸分泌蛋白10;
背景信息:
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP proteins are highly expressed in the mammalian reproductive tract and in the venom secretory ducts of some reptiles. CRISP-10 (cysteine-rich secretory protein 10), also known as CocoaCrisp and Trypsin inhibitor Hl, is a 500 amino acid protein containing 2 LCCL domains, which are thought to function as autonomous folding domains used to construct modular proteins through exon shuffling. CRISP-10 differs from other CRISP proteins in that it does not contain the 10 conserved cysteine residues or ICR domains that are usually conserved throughout the CRISP family.