RTP2 is a 225 amino acid single-pass type III membrane protein whose cell surface expression is dependent on olfactory receptor interaction. RTP2 belongs to the TMEM7 family, playing a role in both the function of odorant receptors and their translocation to the plasma membrane. RTP2 is highly expressed olfactory and vomeronasal organs with low expression in brain. While RTP2 lacks a signal peptide it contains a C-terminal transmembrane domain. The gene encoding RTP2 maps to human chromosome 3q27.3.