基因名:
NAT2
产品别名:
AAC2; NAT-2; PNAT; NAT2; N-acetyltransferase 2; N-acetyltransferase 2; arylamine N-acetyltransferase 2; N-acetyltransferase 2 (arylamine N-acetyltransferase); N-acetyltransferase type 2; arylamide acetylase 2; N-乙酰基转移酶2; N-乙酰转移酶2(NAT2);
背景信息:
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq].