基因名：
AOC1
产品别名：
ABP； ABP1； DAO； DAO1； KAO； AOC1； amine oxidase copper containing 1； amine oxidase copper containing 1； amiloride-sensitive amine oxidase [copper-containing]； amiloride binding protein 1 (amine oxidase (copper-containing))； amiloride-binding protein 1； amiloride-sensitive amine oxidase； amine oxidase copper domain-containing protein 1； diamine oxidase； histaminase； kidney amine oxidase； 二胺氧化酶(ABP1)； 二胺氧化酶(ABP1)真核蛋白； 阿米洛利结合蛋白1；
背景信息：
Amiloride-sensitive amine oxidase (AOC1) belongs to the copper/topaquinone oxidase family. The protein exists as homodimer by disulfide and mainly located in placenta and kidney. AOC1 catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. The activity of this protein can be inhibited by amiloride in a competitive manner. It is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
