基因名:
ACAA1
产品别名:
ACAA; Lnc-Myd88; PTHIO; THIO; ACAA1; acetyl-CoA acyltransferase 1; acetyl-CoA acyltransferase 1; 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA C-myristoyltransferase; acetyl-Coenzyme A acyltransferase 1; beta-ketothiolase; epididymis secretory sperm binding protein; peroxisomal 3-oxoacyl-CoA thiolase; peroxisomal 3-oxoacyl-Coenzyme A thiolase; testicular tissue protein Li 197; 乙酰辅酶A酰基转移酶1; 乙酰辅酶A酰基转移酶1(ACAA1);
背景信息:
ACAA1 is a 424 amino acid member of the thiolase family of enzymes and is involved in lipid metabolism. Localized to the peroxisome, ACAA1 catalyzes the conversion of acyl-CoA and acetyl-CoA to 3-oxoacyl-CoA in the fatty acid oxidation pathway. ACAA1 shows high enzymatic activity in liver, kidney, intestine and white adipose tissue in rats, where it exists as two types, namely type A and type B. Human ACAA1 shares 86% amino acid identity with its rat counterpart, suggesting a conserved function for ACAA1 among different species.