基因名：
ADCYAP1R1
产品别名：
PAC1； PAC1R； PACAPR； PACAPRI； ADCYAP1R1； ADCYAP receptor type I； ADCYAP receptor type I； pituitary adenylate cyclase-activating polypeptide type I receptor； PACAP receptor 1； PACAP type I receptor； PACAP-R1； adenylate cyclase activating polypeptide 1 (pituitary) receptor type I； pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop； pituitary adenylate cyclase-activating polypeptide type 1 receptor； 腺苷酸环化酶激活肽受体1；
背景信息：
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide belonging to the vasoactive intestinal polypeptide/glucagon/ secretin family. It is widely distributed in the body, and a variety of biological actions have been reported. Recent studies have shown that there is a family of PACAP receptors (PACAPRs), and two members of this family have been identified. This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract (By similarity). Belongs to the G-protein coupled receptor 2 family.
