基因名:
ADH1B
产品别名:
ADH2; HEL-S-117; ADH1B; alcohol dehydrogenase 1B (class I), beta polypeptide; alcohol dehydrogenase 1B (class I), beta polypeptide; all-trans-retinol dehydrogenase [NAD(+)] ADH1B; ADH, beta subunit; alcohol dehydrogenase 2 (class I), beta polypeptide; alcohol dehydrogenase subunit beta; aldehyde reductase; epididymis secretory protein Li 117; 乙醇脱氢酶1;
背景信息:
The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]