重组多聚ADP核糖聚合酶(PARP)蛋白

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重组多腺苷二磷酸多聚酶(N端)蛋白
Recombinant PARP1

基因名：

PARP1

产品别名：

ADPRT； ADPRT 1； ADPRT1； ARTD1； PARP； PARP-1； PARS； PPOL； Poly-PARP； pADPRT-1； PARP1； poly(ADP-ribose) polymerase 1； poly(ADP-ribose) polymerase 1； poly [ADP-ribose] polymerase 1； ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)； ADP-ribosyltransferase NAD(+)； ADP-ribosyltransferase diphtheria toxin-like 1； DNA ADP-ribosyltransferase PARP1； NAD(+) ADP-ribosyltransferase 1； poly (ADP-ribose) polymerase family, member 1； poly(ADP-ribose) synthetase； poly(ADP-ribosyl)transferase； poly[ADP-ribose] synthase 1； protein poly-ADP-ribosyltransferase PARP1；多聚ADP核糖聚合酶(PARP)；多腺苷二磷酸多聚酶(N端)；多腺苷二磷酸多聚酶/多聚ADP-核糖聚合酶1；

背景信息：

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008].