基因名:
APLNR
产品别名:
AGTRL1; APJ; APJR; HG11; APLNR; apelin receptor; apelin receptor; apelin receptor; APJ (apelin) receptor; APJ receptor; G protein-coupled receptor APJ; G-protein coupled receptor HG11; HG11 orphan receptor; angiotensin II receptor-like 1; angiotensin receptor-like 1; 爱帕琳肽受体(APLNR); 血管紧张素II受体样蛋白1;
背景信息:
This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq