基因名：
AK2
产品别名：
ADK2； AK2； adenylate kinase 2； adenylate kinase 2； adenylate kinase 2, mitochondrial； ATP-AMP transphosphorylase 2； ATP:AMP phosphotransferase； adenylate kinase isoenzyme 2, mitochondrial； adenylate monophosphate kinase； testis secretory sperm-binding protein Li 220n； 腺苷酸激酶2； 腺苷酸激酶2(AK2)；
背景信息：
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.[provided by RefSeq, Nov 2010]
