基因名：
ANPEP
产品别名：
AP-M； AP-N； APN； CD13； GP150； LAP1； P150； PEPN； hAPN； ANPEP； alanyl aminopeptidase, membrane； alanyl aminopeptidase, membrane； aminopeptidase N； alanyl (membrane) aminopeptidase； aminopeptidase M； membrane alanyl aminopeptidase； microsomal aminopeptidase； myeloid plasma membrane glycoprotein CD13； CD13氨肽酶N； 丙氨酸氨肽酶(AAP)； 丙氨酸氨肽酶(AAP)真核蛋白；
背景信息：
ANPEP gene encodes aminopeptidase N (APN) also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161, is a member of the peptidase M1 family. Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. Probably plays a role in regulating growth and differentiation of early B-lineage cells. It also may play a role in the catabolic pathway of the renin-angiotensin system. It degrades vasoconstricting angiotensin II into angiotensin III and therefore helps to regulate blood pressure.
