基因名：
ANXA2
产品别名：
ANX2； ANX2L4； CAL1H； HEL-S-270； LIP2； LPC2； LPC2D； P36； PAP-IV； ANXA2； annexin A2； annexin A2； annexin A2； annexin II； annexin-2； calpactin I heavy chain； calpactin I heavy polypeptide； calpactin-1 heavy chain； chromobindin 8； epididymis secretory protein Li 270； epididymis secretory sperm binding protein； lipocortin II； placental anticoagulant protein IV； protein I； 膜粘连蛋白 Ⅱ； 膜联蛋白A2(ANXA2)；
背景信息：
Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 is involved in muscular dystrophies. In humans, the up-regulation of ANXA2 is related with colon adenocarcinoma cell differentiation.
