基因名:
ANXA11
产品别名:
ALS23; ANX11; CAP-50; CAP50; IBMWMA; ANXA11; annexin A11; annexin A11; annexin A11; 56 kDa autoantigen; annexin XI; annexin-11; calcyclin-associated annexin 50; epididymis secretory sperm binding protein; 膜粘连蛋白11; 膜联蛋白A11(ANXA11);
背景信息:
The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain, which binds to phospholipids in a Ca2+-dependent manner, and a unique amino terminal region, which may confer binding specificity. The annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. Two forms of Annexin XI, designated A and B, have been identified. Transfection of COS-7 cells with Annexin XI-A, but not Annexin XI-B, causes formation of Annexin XI-associated vesicles.