重组β淀粉样前体蛋白结合蛋白1(X11α)

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Recombinant APBA1
Recombinant amyloid beta precursor protein binding family A member 1 protein

基因名：

APBA1

产品别名：

D9S411E； LIN10； MINT1； X11； X11A； X11ALPHA； APBA1； amyloid beta precursor protein binding family A member 1； amyloid beta precursor protein binding family A member 1； amyloid-beta A4 precursor protein-binding family A member 1； adapter protein X11alpha； adaptor protein X11alpha； amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)； mint-1； neuron-specific X11 protein； neuronal munc18-1-interacting protein 1； phosphotyrosine-binding/-interacting domain (PTB)-bearing protein； β淀粉样前体蛋白结合蛋白1（X11α）；

背景信息：

The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the ∫-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11a (also designated Mint 1), X11Beta (Mint 2) and X11(Mint 3).

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。