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重组存活素(Surv)蛋白
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

重组磷酸化细胞凋亡抑制因子蛋白
Recombinant BIRC5
基因名:

BIRC5


产品别名:

API4; EPR-1; BIRC5; baculoviral IAP repeat containing 5; baculoviral IAP repeat containing 5; baculoviral IAP repeat-containing protein 5; apoptosis inhibitor 4; apoptosis inhibitor survivin; 存活素(Surv); 磷酸化细胞凋亡抑制因子; 细胞凋亡抑制因子; 细胞凋亡抑制因子3α;


背景信息:
Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.
 
 
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