基因名：
FASLG
产品别名：
ALPS1B； APT1LG1； APTL； CD178； CD95-L； CD95L； FASL； TNFSF6； TNLG1A； FASLG； Fas ligand； Fas ligand； tumor necrosis factor ligand superfamily member 6； CD95 ligand； Fas ligand (TNF superfamily, member 6)； apoptosis (APO-1) antigen ligand 1； apoptosis antigen ligand； fas antigen ligand； mutant tumor necrosis factor family member 6； tumor necrosis factor ligand 1A； Fas Ligand（CD178）蛋白； FasL（CD178）；
背景信息：
Fas ligand is also known as FasL, CD178, CD95L, or TNFSF6, is a homotrimeric type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its ability to induce apoptosis in target cells plays an important role in the development, homeostasis, and function of the immune system. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
